The Science

Anthocyanins have a central and critical role in regulating many of the body’s metabolic pathways.
Anthocyanins

Aronia is perhaps the richest source of anthocyanins in the plant kingdom. Anthocyanins have a central and critical role in regulating many of the body's metabolic pathways.

Fat Cells

Anthocyanins have a unique role in controlling fat cell function by up-regulating the release of the hormone adiponectin.

Conditions

Type 2 Diabetes
Obesity 
Metabolic Syndrome 

Cardiovascular Disease / Hypertension
Neurodegenerative and many other inflammatory disorders

All these conditions are associated with low levels of adiponectin – the common factor relating insulin resistance, obesity and inflammation. This makes fat cells a common target for these conditions - and suggests a common therapeutic key. Increasing evidence suggests naturally occurring anthocyanins may be that KEY.

Berryactives Ltd is a science based company. 
We encourage consumers to investigate accumulating evidence of the relationship between an anthocyanin-rich diet and multiple biomarkers of human health.

"In healthy men, consumption of aronia berry (poly)phenols improved endothelial function and modulated gut microbiota composition, indicating that regular aronia consumption has the potential to maintain cardiovascular health in individuals at low risk of cardiovascular disease."  Effects of aronia berry (poly)phenols on vascular function and gut microbiota: a double-blind randomised controlled trial in adult men.  Istas G et al. Am J Clin Nutr 2019;00:1-14

“…the remarkable correlation between coronary artery disease (CAD) and alterations in glucose metabolism has raised the likelihood that atherosclerosis and type 2 diabetes mellitus (T2DM) may share a common biological background.”
Adiponectin: a manifold therapeutic target for metabolic syndrome, diabetes and coronary disease? Fisman EZ, Tenenbaum A. Cardiovascular Diabetology 2014,13:103

“….anthocyanins have a unique therapeutic advantage responsible for the regulation of the adipocyte function. These findings provide a biochemical basis for the use of anthocyanins, which can also have important implications for preventing metabolic syndrome.”
Regulation of Adipocyte Function by Anthocyanins; Possibility of Preventing the Metabolic Syndrome. Tsuda T.J Agric. Food Chem 2008, 56, 642–646

“Epidemiological studies suggest that increased consumption of anthocyanins lowers the risk of T2DM. Many in vitro and in vivo studies also reveal an array of mechanisms through which anthocyanins could prevent or reverse obesity and T2DM-related pathologies including promotion of antioxidant and anti-inflammatory activities, improvement of insulin resistance, and hypolipidemic and hypoglycemic actions”.
The update of anthocyanins on obesity and type 2 diabetes: Experimental evidence and clinical perspectives. Guo.H, Ling W. Rev Endocr Metab Disord 2015 16:1–13

"...(Aronia melanocarpa), a lesser known berry fruit, is one of the richest plant sources of highly interesting phenolic phytochemicals including procyanidins and anthocyanins. The high content as well as the pattern of the phenolic constituents seems to be responsible for the wide range of its potential medicinal and therapeutic effects."
Chokeberry (Aronia melanocarpa) – A Review on the Characteristic Components and Potential Health Effects. Kulling SE et al. Planta Med 2008; 74: 1625–1634

“Polyphenolic compounds from A. melanocarpa berries are characterized by stronger radical-scavenging activity than polyphenols present in other berries”.
“Strong antioxidative properties make it possible that chokeberries (ARONIA) may be effectively used in the prophylaxis and treatment of the health disorders connected with oxidative stress, especially diabetes and cancers“
Chokeberries (Aronia melanocarpa) and their products as a possible means for the prevention and treatment of noncommunicable diseases and unfavourable health effects due to exposure to xenobiotics. Borowska S, Brzoska M. Comprehensive Reviews in Food Science and Food Safety 2016 Vol. 00.

“Long-term consumption of berries and berry products may improve plasma lipid profile and reduce the risk factors of metabolic syndrome and cardiovascular diseases. More research shall be directed to the potential of a berry diet in combating stress and supporting healthy aging. The interaction between berry phenolics and the gut microbiota plays an important role in the bioavailability of berry phenolics and likely contributes to gut health by modifying the gut microbiome.”
Clinical Evidence on potential health benefits of berries. Yang B, Kortesniemi M. Current Opinion in Food Science. 2015 2:39.

“It is also important to emphasize the remarkable position of black chokeberry fruit among other berry crops. The total polyphenols (TP) in A. melanocarpa berries were quantified as higher than for many other remarkable berries, including blueberries, red raspberries, red currant, strawberries and blackberries…….moreover, several mechanisms of action have been identified for a chemopreventive effect of polyphenolic extract of black chokeberry fruit (prevention of oxidation, reduction of oxidative stress, induction of detoxication enzymes, induction of cell cycle arrest apoptosis, regulation of the host immune system, anti-inflammatory activity and changes in cellular signaling) that can multiply their utilization in comparison to other berry crops.”
Fruits of Black Chokeberry (Aronia melanocarpa) in the Prevention of Chronic Diseases. Jurikova T et al. Molecules 2017, 22,944

The aronia berry is one of the richest sources of anthocyanins in the plant kingdom.